Trion-1 GeneralQA - Interaction and Binding: leaderboard

Trion-1 Table 3: 481 protein-sequence questions, with category counts 150, 152, 153 and 26. Scores measure semantic final-answer accuracy. Frontier LLMs, AMix2, BioMatrix and Trion use the common sequence-understanding task. The BioMatrix structure-input and judge footnote applies only to StructureMCQA. MDLM and BDLM remain distinct trained models. Accuracy (%).

Metric: Accuracy (%). Source: arxiv.org. Saturation forecast: Around May 2028. 13 models tracked.

Top models

#ModelScoreOverall rank
1Claude Opus 4.762.5#52
2Claude Opus 4.648.68#65
3GPT-5.546.05#30
4DeepSeek V4 Pro45.39#109
5Qwen 3.7 Max43.42#79
6GPT-OSS-120B38.82#345
7GLM-5.137.5#106

No result here: #5 Claude Opus 5.5, #6 GPT-6 Astra, #7 GPT-6.1 Sol.

Interactive version: theaggregate.ai/benchmark?slug=trion-1-generalqa-interaction-and-binding · How It Works · Data refreshed daily, snapshot 2026-10-25.