SynBio-Reason (Zero-Shot): leaderboard
Metric: Task success rate (%; mean over the procedural test, Cello in-distribution, Cello held-out-part and Literature-91 de novo design splits; generated pysbol3 code must pass all five verification levels; zero-shot prompt with the pysbol3 API reference, greedy decoding). Source: arxiv.org. Saturation forecast: Around 2028. 2 models tracked.
Top models
| # | Model | Score |
|---|---|---|
| 1 | Claude Opus 4.5 (Thinking) | 22.4 |
| 2 | Qwen 3 8B | 7 |
Interactive version: theaggregate.ai/benchmark?slug=synbio-reason-zero-shot · How It Works · Data refreshed daily, snapshot 2026-09-26.