SupraBench - Top-Binder Selection: leaderboard

Top-binder selection in SupraBench (2026), a supramolecular chemistry benchmark: accuracy in percent at choosing the strongest-binding of four candidate guests for a host, zero-shot. Higher is better.

Metric: Accuracy (%) at picking the strongest of four candidate guests for a host (2,264 questions), zero-shot direct prompt. Source: arxiv.org. Saturation forecast: Around August 2027. 8 models tracked.

Top models

#ModelScoreOverall rank
1Gemini 3 Flash49.8#164
2GPT-5.4 Mini42.8#389
3GPT-5.4 Nano41.1#635
4Qwen 3.5 27B40.4#359
5Qwen 3.5 9B37.9#803
6Llama 3.1 70B Instruct33.8#1546
7Llama 3.1 8B Instruct22.8#4246

No result here: #1 Claude Fable 5.2, #2 Gemini 4 Carbon, #5 Claude Opus 5.5.

Interactive version: theaggregate.ai/benchmark?slug=suprabench-top-binder-selection · How It Works · Data refreshed daily, snapshot 2026-11-13.