Structural Biology Open-Ended (Opus 4.6 System Card): leaderboard
Structural Biology Open-Ended results as reported in the Claude Opus 4.6 system card — Anthropic-run evaluation comparing a small set of frontier models.
Metric: Score (%). Source: www-cdn.anthropic.com. Saturation forecast: Around October 2028. 3 models tracked.
Top models
| # | Model | Score | Overall rank |
|---|---|---|---|
| 1 | Claude Opus 4.6 (Thinking) | 28.4 | #63 (Claude Opus 4.6) |
| 2 | Claude Opus 4.5 (Thinking) | 21.2 | #83 (Claude Opus 4.5) |
| 3 | Claude Sonnet 4.5 | 17.9 | #142 |
No result here: #3 Claude Opus 5.5, #6 GPT-6 Astra, #7 GPT-6.1 Sol.
Interactive version: theaggregate.ai/benchmark?slug=structural-biology-open-ended-opus-4-6-system-card · How It Works · Data refreshed daily, snapshot 2026-10-20.