Science's Last Exam - Protocol Planning: leaderboard

Science's Last Exam (SLE, Gen-Verse/AItonomy) runs models as command-line agents (Claude Code or Codex) on 113 v1 research tasks across nine disciplines. Unlike Humanity's Last Exam, which asks closed-book expert questions, SLE grades executed scientific work: protocol plans, scientific code that must pass every check, GUI scientific-software operation and experiment read-outs, with hypothesis discovery run in the DiscoveryRSI runtime over clinical and omics databases. Rows are model API endpoints with the harness and reasoning setting the leaderboard lists. Question access: the task-card, input-data and reference repositories are in private preview and require permission. Protocol Planning: mean task score over 40 tasks (next-action correctness or plan similarity with parameter accuracy, 0-100).

Metric: Mean task score over 40 tasks (0-100). Source: huggingface.co. Saturation forecast: Rough model projection: around 2026. 9 models tracked.

Top models

#ModelScoreOverall rank
1GLM-5.3 Flash (Benchmark Sweep Run: source=Science's Last Exam; harness=Claude Code; hypothesis-discovery runtime=DiscoveryRSI; effort=high; API endpoint; hub-model=zai-org/GLM-5.3-Flash)58
2Kimi K3.1 Pro (Benchmark Sweep Run: source=Science's Last Exam; harness=Claude Code; hypothesis-discovery runtime=DiscoveryRSI; effort=high; API endpoint)58
3GPT-6.1 Sol (Benchmark Sweep Run: source=Science's Last Exam; harness=Codex; hypothesis-discovery runtime=DiscoveryRSI; effort=high; API endpoint)57.3
4Claude Opus 5 (Benchmark Sweep Run: source=Science's Last Exam; harness=Claude Code; hypothesis-discovery runtime=DiscoveryRSI; effort=high; API endpoint)55
5DeepSeek V4.1 Flash (1017) (Benchmark Sweep Run: source=Science's Last Exam; harness=Claude Code; hypothesis-discovery runtime=DiscoveryRSI; effort=high; API endpoint; hub-model=deepseek-ai/DeepSeek-V4.1-Flash-1017)55
6Qwen 3.8 Max (Benchmark Sweep Run: source=Science's Last Exam; harness=Claude Code; hypothesis-discovery runtime=DiscoveryRSI; effort=default; API endpoint; hub-model=Qwen/Qwen3.8-2.4T-A95B)52
7MiMo-V2.6-Pro-MOPD (Benchmark Sweep Run: source=Science's Last Exam; harness=Claude Code; hypothesis-discovery runtime=DiscoveryRSI; effort=high; API endpoint; hub-model=XiaomiMiMo/MiMo-V2.6-Pro-MOPD)49
8Gemini 4 Argon (Benchmark Sweep Run: source=Science's Last Exam; harness=Codex; hypothesis-discovery runtime=DiscoveryRSI; effort=default; API endpoint)46.1
9MiniMax-M3 (Benchmark Sweep Run: source=Science's Last Exam; harness=Claude Code; hypothesis-discovery runtime=DiscoveryRSI; effort=high; API endpoint; hub-model=MiniMaxAI/MiniMax-M3)43

Interactive version: theaggregate.ai/benchmark?slug=science-s-last-exam-protocol-planning · How It Works · Data refreshed daily, snapshot 2026-11-12.