RefusalBench: leaderboard

Frontier large language models are increasingly deployed as orchestration backbones for biological research workflows, yet no shared evidence base exists for comparing their refusal behaviour on legitimate research prompts. RefusalBench, introduced here, is a matched-triple benchmark of 141 prompts in 47 bundles that holds task framing constant while varying only biological risk tier (benign, bord

Metric: Strict Refusal Rate (self-reported). Source: benchmarklist.com. Saturation forecast: Estimated already saturated. 19 models tracked.

Top models

#ModelScoreOverall rank
1Claude Opus 4.70.1#49
2GPT-4.1 Nano0.2#731
3Gemini 2.5 Pro0.4#152
4Gemini 2.5 Flash0.6#245
5GPT-4.1 Mini0.6#355
6Claude Opus 4.51.2#83
7Grok 4.201.3#175
8GPT-4.11.4#248
9GPT-4o2.1#343
10DeepSeek R118.4#251
11Qwen 2.5 Max29.8#416
12DeepSeek V3 (0324)47.5#340
13Mistral Large 2 (Jul)87.2#484
14Command A94.6#508

No result here: #3 Claude Opus 5.5, #6 GPT-6 Astra, #7 GPT-6.1 Sol.

Interactive version: theaggregate.ai/benchmark?slug=refusalbench · How It Works · Data refreshed daily, snapshot 2026-10-20.