ProteinGym Hard: leaderboard
Hard ProteinGym subset reported in Anthropic's Claude Opus 4.8 system card.
Metric: Rank correlation (self-reported). Source: benchmarklist.com. Status: saturation imminent. 10 models tracked.
Top models
| # | Model | Score |
|---|---|---|
| 1 | Claude Opus 5 | 47.7 |
| 2 | Claude Mythos 5 | 45.8 |
| 3 | Claude Mythos Preview | 43.1 |
| 4 | Claude Opus 4.8 | 40 |
| 5 | Claude Opus 4.7 | 37.7 |
| 6 | Gemini 3.1 Pro (Preview) | 37 |
| 7 | Claude Sonnet 5 | 36.6 |
| 8 | GPT-5.6 Sol | 35.5 |
| 9 | Claude Sonnet 4.6 | 35 |
Interactive version: theaggregate.ai/benchmark?slug=proteingym-hard · How It Works · Data refreshed daily, snapshot 2026-09-05.