ProteinGym: leaderboard

Protein fitness prediction from deep mutational scans: about 2.7M substitutions across 217 DMS assays and 300k indels across 74 assays; Marks Lab, Harvard Medical School, NeurIPS 2023; Spearman.

Source: github.com.

Interactive version: theaggregate.ai/benchmark?slug=proteingym · How It Works · Data refreshed daily, snapshot 2026-09-05.