PhysDox: leaderboard

PhysDox (2026) tests whether LLMs can audit biomedical physiological-sensing protocols for physical feasibility on a 683-protocol expert-curated Gold set spanning six sensing domains. The headline is the macro-F1 (0-100) of classifying each protocol as valid, minor issue or fatal violation under zero-shot prompting; higher is better.

Metric: Stage-1 severity-detection macro-F1 (0-100) on the 683-protocol expert-curated Gold set of biomedical physiological-sensing protocols (six domains): classify each protocol as valid, minor issue or fatal physical-feasibility violation; zero-shot prompting, temperature 0.1, JSON output with retries for malformed responses; higher is better. Source: arxiv.org. Saturation forecast: Around 2029. 6 models tracked.

Top models

#ModelScoreOverall rank
1Claude Opus 4.751.7#79
2DeepSeek V4 Flash45.8#258
3MiMo-V2.5-Pro45.6#279
4DeepSeek V4 Pro44.6#188
5MiMo-V2.543.9#354
6GPT-5.537.8#49

No result here: #1 Claude Fable 5.2, #2 Gemini 4 Carbon, #5 Claude Opus 5.5.

Interactive version: theaggregate.ai/benchmark?slug=physdox · How It Works · Data refreshed daily, snapshot 2026-11-13.