Organic Chemistry (Anthropic): leaderboard

Anthropic system-card organic chemistry evaluation, testing reaction and molecule reasoning.

Metric: Score (%). Source: www-cdn.anthropic.com. Saturation forecast: Around January 2027. 4 models tracked.

Top models

#ModelScoreOverall rank
1Claude Mythos Preview86.5#4
2Claude Opus 4.886.2#37
3Claude Opus 4.777.2#49
4Claude Sonnet 4.653.1#90

No result here: #3 Claude Opus 5.5, #6 GPT-6 Astra, #7 GPT-6.1 Sol.

Interactive version: theaggregate.ai/benchmark?slug=organic-chemistry-anthropic · How It Works · Data refreshed daily, snapshot 2026-10-20.