OpenAI GPT-5.6 System Card - Biology Refusal - Dual Use: leaderboard

Biology Model Refusal Evaluation table of OpenAI's GPT-5.6 System Card (Deployment Safety Hub, 2026-07-09): share of responses to dual-use biology prompts graded not unsafe, model responses only without monitors. Percent (the card prints 0-1), higher is better. GPT-5.2, 5.4 and 5.5 Thinking and GPT-5.6 Sol, Terra and Luna.

Metric: Not unsafe rate (%). Source: deploymentsafety.openai.com. Saturation forecast: Estimated already saturated. 6 models tracked.

Top models

#ModelScoreOverall rank
1GPT-5.4 (Thinking)95.5#83 (GPT-5.4)
2GPT-5.592.6#33
3GPT-5.6 Luna92.6#79
4GPT-5.2 (Thinking)92.1#115 (GPT-5.2)
5GPT-5.6 Sol91.1#22
6GPT-5.6 Terra91.1#40

No result here: #3 Claude Opus 5.5, #6 GPT-6 Astra, #7 GPT-6.1 Sol.

Interactive version: theaggregate.ai/benchmark?slug=openai-gpt-5-6-system-card-biology-refusal-dual-use · How It Works · Data refreshed daily, snapshot 2026-11-05.