OpenAI GPT-5.5 System Card - Hard Negative Protein Binding Prediction: leaderboard
Biosecurity capability slice from OpenAI's GPT-5.5 system card — hard-negative protein-binding prediction; OpenAI-run frontier comparison.
Metric: pass@4 (%). Source: deploymentsafety.openai.com. 3 models tracked.
Top models
| # | Model | Score | Overall rank |
|---|---|---|---|
| 1 | GPT-5.4 (Thinking) | 3.46 | #79 (GPT-5.4) |
| 2 | GPT-5.5 | 1.48 | #31 |
| 3 | GPT-5.5 Pro | 0 | #17 |
Interactive version: theaggregate.ai/benchmark?slug=openai-gpt-5-5-system-card-hard-negative-protein-binding-prediction · How It Works · Data refreshed daily, snapshot 2026-10-20.