Omni-I2C (SMILES) - Tanimoto Similarity: leaderboard
Metric: Tanimoto similarity (0-100) between Morgan fingerprints of the generated and reference SMILES over the 100 chemical-structure images; greedy decoding; higher is better. Source: arxiv.org. Saturation forecast: Around January 2027. 13 models tracked.
Top models
| # | Model | Score | Overall rank |
|---|---|---|---|
| 1 | Qwen 3 VL 235B A22B Instruct | 66.9 | #264 |
| 2 | Claude Sonnet 4.5 | 59.4 | #138 |
| 3 | Qwen 3 VL 8B Instruct | 53.4 | #401 |
| 4 | Qwen 3 VL 32B Instruct | 51.6 | #276 |
| 5 | GPT-5.1 | 49 | #131 |
| 6 | Gemini 3 Pro | 48 | #77 |
| 7 | Qwen 2.5 VL 72B Instruct | 29.8 | #364 |
| 8 | Gemma 3 27B (IT) | 23.1 | #509 |
| 9 | Qwen 2.5 VL 7B Instruct | 15.3 | #643 |
No result here: #3 Claude Opus 5.5, #5 GPT-6 Astra, #8 Claude Fable 5.1.
Interactive version: theaggregate.ai/benchmark?slug=omni-i2c-smiles-tanimoto-similarity · How It Works · Data refreshed daily, snapshot 2026-10-11.