MTBBench-Multimodal: leaderboard

The multimodal track of MTBBench (Vasilev et al., 2025), a simulated molecular tumor board for head-and-neck cancer: over a multi-turn dialogue an LLM agent requests H&E and IHC slide images, hematology reports and surgical notes for 26 HANCOCK patients and answers 390 GPT-4o-drafted, expert-reviewed true/false and six-option multiple-choice questions, without tools. The score is the unweighted mean of the digital-pathology, hematology and outcome-and-recurrence accuracies in percent; higher is better.

Metric: Accuracy (%; unweighted mean of the three task accuracies; 26 head-and-neck cancer patients from HANCOCK, 390 true/false and six-option multiple-choice questions; multi-turn agent that requests patient files, no tools). Source: arxiv.org. Saturation forecast: Estimated already saturated. 10 models tracked.

Top models

#ModelScoreOverall rank
1InternVL3-78B69.1#733
2GPT-4o (2024-08-06)66.7#731
3O4 Mini (2025-04-16)64.3#362
4InternVL3-38B63.5#905

No result here: #1 Claude Fable 5.2, #2 Gemini 4 Carbon, #5 Claude Opus 5.5.

Interactive version: theaggregate.ai/benchmark?slug=mtbbench-multimodal · How It Works · Data refreshed daily, snapshot 2026-11-12.