Longitudinal MRI Progression Reasoning: leaderboard

Final disease-progression accuracy for 16 general and medically specialized vision-language models on zero-shot multi-sequence, multi-view longitudinal MRI inputs. This is the main benchmark evaluation, separate from the UCSF-GBM agentic-workflow subset.

Metric: Final Accuracy (%, zero-shot multi-view MRI). Source: arxiv.org. Saturation forecast: Not forecast. 16 models tracked.

Top models

#ModelScoreOverall rank
1Gemini 3 Pro35.1#80
2O4 Mini32.18#180
3GPT-4o32#343
4Llama 4 Scout28.47#656
5Llama 4 Maverick26.84#464
6Qwen 3 VL 8B Instruct24.31#420
7Gemini 2.5 Pro23.66#152
8Gemini 2.5 Flash23.57#245
9MedGemma-4B-IT23.5#853
10Gemini 3 Flash22.3#99
11GPT-5.221.2#110

No result here: #3 Claude Opus 5.5, #6 GPT-6 Astra, #7 GPT-6.1 Sol.

Interactive version: theaggregate.ai/benchmark?slug=longitudinal-mri-progression-reasoning · How It Works · Data refreshed daily, snapshot 2026-10-20.