HypoArena - Biomedical Science: leaderboard

The biomedical science domain of HypoArena (2026), 244 cases: the Bradley-Terry-Davidson rating, anchored at 1500 with no fixed maximum, from pairwise judgments by seed-2.0-pro of the hypothesis sets each model proposes. Higher is better.

Metric: Rating on the 244 biomedical science cases: Bradley-Terry-Davidson rating (base 1500, open-ended) from reference-independent pairwise judgments by seed-2.0-pro, both presentation orders, with the source-derived reference hypothesis set as an anonymous competitor; baseline single-pass generation; higher is better. Source: arxiv.org. Saturation forecast: Around September 2027. 15 models tracked.

Top models

#ModelScoreOverall rank
1GPT-5.4 (High)1627.2#123 (GPT-5.4)
2Claude Opus 4.6 (High)1608.9#102 (Claude Opus 4.6)
3Claude Sonnet 4.6 (High)1601.2#161 (Claude Sonnet 4.6)
4GLM-5.11592.8#179
5Kimi K2.61570.5#178
6DeepSeek V4 Pro (High)1525#188 (DeepSeek V4 Pro)
7MiniMax-M2.71508.3#518
8GLM-51469.1#260
9DeepSeek V4 Flash (High)1464.3#258 (DeepSeek V4 Flash)
10MiniMax-M2.51458.4#582
11Gemini 3.1 Pro (Preview) (High)1429.9#94 (Gemini 3.1 Pro (Preview))
12GPT-5.4 Mini (High)1424#389 (GPT-5.4 Mini)
13Gemini 3 Flash (High)1420#164 (Gemini 3 Flash)
14Kimi K2.5 (Thinking)1281.8#256 (Kimi K2.5)

No result here: #1 Claude Fable 5.2, #2 Gemini 4 Carbon, #5 Claude Opus 5.5.

Interactive version: theaggregate.ai/benchmark?slug=hypoarena-biomedical-science · How It Works · Data refreshed daily, snapshot 2026-11-13.