GenomeQA (Multiple Choice) - TFBS Prediction: leaderboard

Metric: Accuracy (%) on the four-option (chance 25) TFBS Prediction questions of GenomeQA (raw DNA sequences as input), one fixed system prompt, thinking enabled where supported; higher is better. Source: arxiv.org. Saturation forecast: Around April 2027. 6 models tracked.

Top models

#ModelScore
1Gemini 3 Pro (Preview)59
2GPT-5.1 (Thinking)50.2
3Grok 4.1 Fast (Reasoning)48.4
4Claude Sonnet 4.5 (Thinking)48
5Qwen 3 Max (Preview) (Thinking)45.2
6Llama 4 Maverick Instruct34.4

Interactive version: theaggregate.ai/benchmark?slug=genomeqa-multiple-choice-tfbs-prediction · How It Works · Data refreshed daily, snapshot 2026-10-07.