GenomeQA (Binary Choice) - Histone Mark Prediction: leaderboard
Metric: Accuracy (%) on the two-option (chance 50) Histone Mark Prediction questions of GenomeQA (raw DNA sequences as input), one fixed system prompt, thinking enabled where supported; higher is better. Source: arxiv.org. Saturation forecast: Around 2029. 6 models tracked.
Top models
| # | Model | Score |
|---|---|---|
| 1 | Gemini 3 Pro (Preview) | 57.2 |
| 2 | Claude Sonnet 4.5 (Thinking) | 53.8 |
| 3 | Grok 4.1 Fast (Reasoning) | 53.2 |
| 4 | GPT-5.1 (Thinking) | 53.2 |
| 5 | Llama 4 Maverick Instruct | 52.6 |
| 6 | Qwen 3 Max (Preview) (Thinking) | 51.2 |
Interactive version: theaggregate.ai/benchmark?slug=genomeqa-binary-choice-histone-mark-prediction · How It Works · Data refreshed daily, snapshot 2026-10-07.