ChemRxn-Bench - Direct Strict Reaction F1: leaderboard

603figures; exact normalized reactant/product sets with stereochemistry and one-to-one multiset matching. Per-figure macroF1; missing/malformed/tool-error/timeout predictions receive zero extraction credit. Native Direct/BarePi/RxnMiner harness kept separate; one-hour budget and Qwen thinking apply RxnMiner config only.

Metric: Macro F1 (%). Source: arxiv.org. Saturation forecast: Around July 2028. 5 models tracked.

Top models

#ModelScoreOverall rank
1Kimi K340#35
2Seed 2.1 Pro34#73
3GLM-5.3 Flash31#77
4Qwen3.8-Flash-Next21#76
5DeepSeek V4.1 Flash16#37

No result here: #3 Claude Opus 5.5, #6 GPT-6 Astra, #7 GPT-6.1 Sol.

Interactive version: theaggregate.ai/benchmark?slug=chemrxn-bench-direct-strict-reaction-f1 · How It Works · Data refreshed daily, snapshot 2026-11-05.