ChemGraph - Multi-Agent: leaderboard
ChemGraph Leaderboard (Argonne) multi-agent workflow: several specialised agents coordinate chemistry tool calls to answer the same 40 computational-chemistry queries in 12 categories. A structured judge marks each answer correct within 5% relative tolerance; accuracy % from the latest published evaluation run, higher is better.
Metric: Accuracy (%, 40 computational-chemistry queries). Source: huggingface.co. Saturation forecast: Estimated already saturated. 31 models tracked.
Top models
| # | Model | Score | Overall rank |
|---|---|---|---|
| 1 | Claude Sonnet 4.5 | 100 | #148 |
| 2 | Gemini 2.5 Flash | 97.5 | #255 |
| 3 | GPT-5.4 | 97.5 | #83 |
| 4 | Claude Haiku 4.5 | 97.5 | #287 |
| 5 | Claude Opus 4.7 | 97.5 | #51 |
| 6 | Claude Opus 4.8 | 97.5 | #39 |
| 7 | Claude Sonnet 5 | 97.5 | #65 |
| 8 | GPT-4o | 95 | #357 |
| 9 | Nemotron 3 Ultra | 95 | #245 |
| 10 | Claude Sonnet 4.6 | 92.5 | #94 |
| 11 | GPT-5.5 | 92.5 | #33 |
| 12 | GPT-4.1 | 90 | #258 |
| 13 | Inkling | 87.5 | #144 |
| 14 | GPT-5.6 Terra | 85 | #40 |
| 15 | O3 Mini | 85 | #282 |
No result here: #3 Claude Opus 5.5, #6 GPT-6 Astra, #7 GPT-6.1 Sol.
Interactive version: theaggregate.ai/benchmark?slug=chemgraph-multi-agent · How It Works · Data refreshed daily, snapshot 2026-11-05.