BioSecBench-Function: leaderboard

BioSecBench-Function evaluates text-based recovery of biosecurity-relevant biological function from real experimental data, assays, structures, and sequences. The pinned metric is Endpoint pass rate (%), measuring deterministic agreement with published experimental ground truth. The benchmark uses restricted-access evaluations and is source-attributed. Source: BenchmarkList’s attributed result table.

Metric: Endpoint pass rate (%). Source: benchmarklist.com. Saturation forecast: Around 2030. 4 models tracked.

Top models

#ModelScoreOverall rank
1GPT-6 Astra (Max)46#6 (GPT-6 Astra)
2Claude Opus 5 (Max)44.8#16 (Claude Opus 5)
3Grok 4.7 (xHigh)43.3#26 (Grok 4.7)
4Grok 4.6 (High)39.9#29 (Grok 4.6)

No result here: #3 Claude Opus 5.5, #7 GPT-6.1 Sol, #9 Gemini 4 Argon.

Interactive version: theaggregate.ai/benchmark?slug=biosecbench-function · How It Works · Data refreshed daily, snapshot 2026-11-05.