BioMedHop (Direct Prompting) - Path-based Reasoning: leaderboard

The Path-based Reasoning family of BioMedHop (Tan et al., 2026): recover the disease hidden inside a typed five-node SPOKE metapath from its endpoints and relation descriptions. The score is the mean of multiple-choice and alias-normalised open-answer accuracy in percent; higher is better. Direct prompting without retrieved evidence.

Metric: Accuracy (%; mean of multiple-choice accuracy and alias-normalised open-answer accuracy on Path-based Reasoning (the hidden disease on a typed five-node SPOKE metapath); stratified evaluation subsets of the 10,045 instances; direct input-output prompting with no retrieved evidence (the paper's IO baseline), temperature 0, at most 1,024 output tokens). Source: arxiv.org. Saturation forecast: Around 2030. 9 models tracked.

Top models

#ModelScoreOverall rank
1GPT-4 Turbo26.1#1002
2Claude 3.7 Sonnet25.5#455
3Gemini 2.5 Pro25.4#262
4Qwen 3 Next 80B A3B Instruct23.5#763
5Claude 3.5 Haiku21.4#1563
6GPT-4o Mini19.8#1627
7MiMo-V2.5-Pro19.5#274
8Qwen 3 4B16#2297

No result here: #1 Claude Fable 5.2, #2 Gemini 4 Carbon, #5 Claude Opus 5.5.

Interactive version: theaggregate.ai/benchmark?slug=biomedhop-direct-prompting-path-based-reasoning · How It Works · Data refreshed daily, snapshot 2026-11-12.