BioMedHop (Direct Prompting) - Entity Pair Matching: leaderboard

The Entity Pair Matching family of BioMedHop (Tan et al., 2026): name the biomedical entity, such as a gene, compound or symptom, that two anchor entities share in the Monarch knowledge graph. The score is the mean of multiple-choice and alias-normalised open-answer accuracy in percent; higher is better. Direct prompting without retrieved evidence.

Metric: Accuracy (%; mean of multiple-choice accuracy and alias-normalised open-answer accuracy on Entity Pair Matching (the shared biomedical neighbour of two anchor entities); stratified evaluation subsets of the 10,045 instances; direct input-output prompting with no retrieved evidence (the paper's IO baseline), temperature 0, at most 1,024 output tokens). Source: arxiv.org. Saturation forecast: Around 2030. 9 models tracked.

Top models

#ModelScoreOverall rank
1Gemini 2.5 Pro13.3#262
2GPT-4 Turbo12.7#1002
3Claude 3.7 Sonnet12.4#455
4Qwen 3 Next 80B A3B Instruct10.8#763
5MiMo-V2.5-Pro9.4#274
6Claude 3.5 Haiku8.9#1563
7GPT-4o Mini7.8#1627
8Qwen 3 4B5.9#2297

No result here: #1 Claude Fable 5.2, #2 Gemini 4 Carbon, #5 Claude Opus 5.5.

Interactive version: theaggregate.ai/benchmark?slug=biomedhop-direct-prompting-entity-pair-matching · How It Works · Data refreshed daily, snapshot 2026-11-12.