BioMedHop (Direct Prompting): leaderboard

Multi-hop biomedical question answering over knowledge-graph motifs from Monarch and SPOKE, with multiple-choice, open-answer and counting questions in four task families; BioMedHop (Tan et al., 2026). The score is the mean of the four family scores in percent, where each entity family averages multiple-choice and open-answer accuracy; higher is better. The model answers from the question alone with direct prompting, without the knowledge-graph, literature or web evidence the benchmark can supply.

Metric: Overall accuracy (%; mean of the four task-family scores, which are MCQ/open-answer accuracy averages and exact-count accuracy; stratified evaluation subsets of the 10,045 instances; direct input-output prompting with no retrieved evidence (the paper's IO baseline), temperature 0, at most 1,024 output tokens). Source: arxiv.org. Saturation forecast: Around 2030. 9 models tracked.

Top models

#ModelScoreOverall rank
1Gemini 2.5 Pro18.6#262
2GPT-4 Turbo18.2#1002
3Claude 3.7 Sonnet17.8#455
4Qwen 3 Next 80B A3B Instruct16.1#763
5Claude 3.5 Haiku14.5#1563
6MiMo-V2.5-Pro13.7#274
7GPT-4o Mini13.2#1627
8Qwen 3 4B9.3#2297

No result here: #1 Claude Fable 5.2, #2 Gemini 4 Carbon, #5 Claude Opus 5.5.

Interactive version: theaggregate.ai/benchmark?slug=biomedhop-direct-prompting · How It Works · Data refreshed daily, snapshot 2026-11-12.