Benchmarks.bio - TxBench-OD: leaderboard

Pass rate on TxBench oligonucleotide-discovery tasks (`tx_oligo_v1`, 113 evals) from Benchmarks.bio's agentic biology suite, run on the `pi` harness.

Metric: Pass Rate (%). Source: benchmarks.bio. Saturation forecast: Around March 2028. 13 models tracked.

Top models

#ModelScoreOverall rank
1GPT-6 Astra55.46#6
2Claude Opus 548.08#16
3Grok 4.643.95#29
4Claude Opus 4.839.88#39
5Gemini 3.7 Flash39.53#24
6Claude Sonnet 539.29#65
7Gemini 3.5 Flash38.64#66
8Grok 4.538.35#54
9GPT-5.6 Sol34.51#22
10DeepSeek V4.1 Flash33.92#37
11GPT-5.533.63#33
12GPT-5.6 Terra33.33#40
13GPT-5.6 Luna23.89#79

No result here: #3 Claude Opus 5.5, #7 GPT-6.1 Sol, #9 Gemini 4 Argon.

Interactive version: theaggregate.ai/benchmark?slug=benchmarks-bio-txbench-od · How It Works · Data refreshed daily, snapshot 2026-11-05.