Benchmarks.bio - EpiBench: leaderboard
Benchmarks.bio epigenomics benchmark covering real assays such as chromatin accessibility, binding, and methylation analyses with deterministic graders.
Metric: Pass Rate (%). Source: benchmarks.bio. Saturation forecast: Around May 2028. 12 models tracked.
Top models
| # | Model | Score | Overall rank |
|---|---|---|---|
| 1 | GPT-5.5 | 44.97 | #31 |
| 2 | GPT-5.4 | 38.99 | #79 |
| 3 | Claude Opus 4.8 | 38.99 | #37 |
| 4 | Claude Opus 5 | 35.22 | #12 |
| 5 | Claude Opus 4.7 | 31.45 | #49 |
| 6 | Claude Opus 4.6 | 30.5 | #63 |
| 7 | Gemini 3.5 Flash | 28.93 | #60 |
| 8 | Gemini 3.1 Pro (Preview) | 27.36 | #58 |
| 9 | Kimi K2.6 | 24.53 | #104 |
| 10 | Claude Sonnet 4.6 | 22.64 | #90 |
| 11 | Grok 4.20 0309 (Reasoning) | 22.33 | #112 (Grok 4.20 0309) |
| 12 | Grok 4.3 | 12.58 | #188 |
No result here: #3 Claude Opus 5.5, #6 GPT-6 Astra, #7 GPT-6.1 Sol.
Interactive version: theaggregate.ai/benchmark?slug=benchmarks-bio-epibench · How It Works · Data refreshed daily, snapshot 2026-10-20.