Benchmarks.bio - EpiBench: leaderboard
Benchmarks.bio epigenomics benchmark covering real assays such as chromatin accessibility, binding, and methylation analyses with deterministic graders.
Metric: Pass Rate (%). Source: benchmarks.bio. Status: years away from saturation. 12 models tracked.
Top models
| # | Model | Score |
|---|---|---|
| 1 | GPT-5.5 | 44.97 |
| 2 | GPT-5.4 | 38.99 |
| 3 | Claude Opus 4.8 | 38.99 |
| 4 | Claude Opus 5 | 35.22 |
| 5 | Claude Opus 4.7 | 31.45 |
| 6 | Claude Opus 4.6 | 30.5 |
| 7 | Gemini 3.5 Flash | 28.93 |
| 8 | Gemini 3.1 Pro (Preview) | 27.36 |
| 9 | Kimi K2.6 | 24.53 |
| 10 | Claude Sonnet 4.6 | 22.64 |
| 11 | Grok 4.20 0309 (Reasoning) | 22.33 |
| 12 | Grok 4.3 | 12.58 |
Interactive version: theaggregate.ai/benchmark?slug=benchmarks-bio-epibench · How It Works · Data refreshed daily, snapshot 2026-09-05.