Benchmarks.bio - BioSecBench-Refusal: leaderboard

BioSecBench-Refusal (benchmarks.bio) — biosecurity refusal and over-refusal benchmark; red-team prompts that should be refused plus routine biology work that should be answered, scored as combined pass rate.

Metric: Pass Rate (%). Source: benchmarks.bio. Saturation forecast: Not forecast. 19 models tracked.

Top models

#ModelScoreOverall rank
1Grok 4.664.2#26
2Gemini 3.5 Flash51.5#60
3GPT-5.445.7#79
4GPT-6 Astra44.6#6
5Claude Sonnet 4.643.5#90
6Gemini 3.1 Pro (Preview)43#58
7GPT-5.6 Sol39.5#19
8Claude Opus 4.639#63
9GPT-5.537.1#31
10Claude Opus 4.736.7#49
11GPT-5.6 Terra34.3#41
12GPT-5.6 Luna33.3#68
13Claude Sonnet 530.1#57
14Claude Opus 529.4#12
15Claude Opus 4.828.6#37

No result here: #3 Claude Opus 5.5, #7 GPT-6.1 Sol, #8 Gemini 4 Argon.

Interactive version: theaggregate.ai/benchmark?slug=benchmarks-bio-biosecbench-refusal · How It Works · Data refreshed daily, snapshot 2026-10-20.